論文・学会

論文

サイフューズのプラットフォーム技術である「三次元細胞積層技術」に関して多数公開されている、国内外の論文情報をご紹介します。

Review

Progress in scaffold-free bioprinting for cardiovascular medicine.
Moldovan NI. J Cell Mol Med. 2018 Mar 13. [Epub ahead of print] Review.

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Principles of the Kenzan Method for Robotic Cell Spheroid-Based Three-Dimensional Bioprinting.
Moldovan NI, Hibino N, Nakayama K. Tissue Eng Part B Rev. 2017 Jun;23(3):237-244.

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3D bioprinting using stem cells.
Ong CS, Yesantharao P, Huang CY, Mattson G, Boktor J, Fukunishi T, Zhang H, Hibino N. Pediatr Res. 2018 Jan;83(1-2):223-231. Epub 2017 Nov 1. Review.

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Comparison of biomaterial-dependent and independent bioprinting methods for cardiovascular medicine.
Leni Moldovan, Clifford M. Babbeya, Michael P. Murphya, and Nicanor I. Moldovanc, Current Opinion in Biomedical Engineering 2017, 2:124–131.

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Liver

In vivo and ex vivo methods of growing a liver bud through tissue connection.
Yanagi Y, Nakayama K, Taguchi T, Enosawa S, Tamura T, Yoshimaru K, Matsuura T, Hayashida M, Kohashi K, Oda Y, Yamaza T, Kobayashi E. Sci Rep. 2017 Oct 26;7(1):14085.

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Neural

The efficacy of a scaffold-free Bio 3D conduit developed from human fibroblasts on peripheral nerve regeneration in a rat sciatic nerve model.
Yurie H, Ikeguchi R, Aoyama T, Kaizawa Y, Tajino J, Ito A, Ohta S, Oda H, Takeuchi H, Akieda S, Tsuji M, Nakayama K, Matsuda S. PLoS One. 2017 Feb 13; 12(2):e0171448.

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Cardiac tissue

Creation of Cardiac Tissue Exhibiting Mechanical Integration of Spheroids Using 3D Bioprinting.
Ong CS, Fukunishi T, Nashed A, Blazeski A, Zhang H, Hardy S, DiSilvestre D, Vricella L, Conte J, Tung L, Tomaselli G, Hibino N. J Vis Exp. 2017 Jul 2;(125). doi: 10.3791/55438.

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Biomaterial-Free Three-Dimensional Bioprinting of Cardiac Tissue using Human Induced Pluripotent Stem Cell Derived Cardiomyocytes.
Ong CS, Fukunishi T, Zhang H, Huang CY, Nashed A, Blazeski A, DiSilvestre D, Vricella L, Conte J, Tung L, Tomaselli GF, Hibino N. Sci Rep. 2017 Jul 4;7(1):4566.

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Vascular

iPSC-Derived Vascular Cell Spheroids as Building Blocks for Scaffold-Free Biofabrication.
Moldovan L, Barnard A, Gil CH, Lin Y, Grant MB, Yoder MC, Prasain N, Moldovan NI. Biotechnol J. 2017 Dec; 12 (12). Epub 2017 Nov 14.

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Scaffold-Free Tubular Tissues Created by a Bio-3D Printer Undergo Remodeling and Endothelialization when Implanted in Rat Aortae.
Itoh M, Nakayama K, Noguchi R, Kamohara K, Furukawa K, Uchihashi K, Toda S, Oyama J, Node K, Morita S. PLoS One. 2015 Sep 1;10(9):e0136681. eCollection 2015. Erratum in: PLoS One. 2015; 10(12):e0145971.

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Bone cartilage

A preliminary study of osteochondral regeneration using a scaffold-free three-dimensional construct of porcine adipose tissue-derived mesenchymal stem cells.
Murata D, Tokunaga S, Tamura T, Kawaguchi H, Miyoshi N, Fujiki M, Nakayama K, Misumi K. J Orthop Surg Res. 2015 Mar 18;10:35.

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Simultaneous regeneration of full-thickness cartilage and subchondral bone defects in vivo using a three-dimensional scaffold-free autologous construct derived from high-density bone marrow-derived mesenchymal stem cells.
Ishihara K, Nakayama K, Akieda S, Matsuda S, Iwamoto Y. J Orthop Surg Res. 2014 Oct 14;9:98.

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学会

サイフューズのプラットフォーム技術である「三次元細胞積層技術」に関する発表が行われた学会の情報をご紹介します。

“HUMAN URETHRA-ENGINEERED WITH HUMAN MESENCHYMAL STEM CELL WITH MATURATION BY REARRANGEMENT OF CELLS FOR SELF-ORGANIZATION – NEWLY DEVELOPED SCAFFOLD-FREE THREE-DIMENSIONAL BIO-PRINTER”

Yamamoto, T. et al., Poster Presentation at American Urology Association Annual Meeting 2015, May 2015 – San Diego
 This presentation was selected as the BEST POSTER.


“Scaffold-Free Trachea Tissue Engineering Using Bioprinting”

Machino, R et al., Poster Presentation at American Thoracic Society 2015 International Conference, May 2015 – Denver

バイオ3Dプリンターで作製したヒト肝臓構造体が高い薬物代謝機能を長期間持続する

長尾 他, 日本薬学会第136年回ポスタープレゼンテーション

バイオ 3Dプリンティング技術による機能的ヒト3D肝臓組織構築とその応用可能性

長尾 他 第52回日本肝臓学会総会一般口演:日本肝臓学会抄録を掲載